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Ready-to-Fill Polymer Syringe with Tapered Needle


PLAJEX™ Ready-to-Fill Polymer Syringe with Tapered Needle

PLAJEX™ Ready-to-Fill Polymer Syringes with Tapered Needles offer the better injectability without compromising patient comfort for pharmaceutical manufacturers who need to overcome injectability problems associated with highly viscous concentrated formulations1.


Ready-to-Fill Polymer Syringes with Tapered Needle

Integrating a proprietary tapered needle technology with a robust 1ml long silicone oil-free polymer syringe, Terumo’s advanced syringe system reduces injection forces without compromising patient comfort. Featuring a polymer-based barrel with excellent strength and clarity, and Terumo’s proprietary i-coatingTM technology on the plunger stopper, the silicone oil-free syringe system is designed to preserve sensitive biotherapeutics2.

PLAJEX™ Ready-to-Fill Polymer Syringes with Tapered Needles offer the quality and supply reliability needed to meet parenteral delivery challenges and product commercialization goals. 

Patient comfort and quality 

  • Carefully crafted tapered needle allows a proven reduction in the necessary injection force, especially for highly viscous non-Newtonian fluids such as some monoclonal antibodies1
  • 29G at the point of patient contact, 24G at the syringe tip
  • Advanced Cyclo Olefin Polymer (COP) syringe moulded for excellent strength and clarity, the syringe is silicone oil-free, tungsten-free, and adhesive-free
  • Lower interactions with proteins, COP barrel ready for today’s advanced biotherapeutics2
  • Integrated plunger stopper featuring Terumo's proprietary i-coating™ technology provides a consistent and predictable gliding force

Striving for global presence

  • Compatible with certain add-on devices3,4 (autoinjector, needle safety device) 
  • Syinges are steam sterilized, nested, and ready for filling and finishing in controlled environments
  • Proven track record of reliable supply assured by global operating company

General specifications

Specification Description
Syringe barrel materialCyclo Olefin Polymer (COP)
Syringe size

1 ml long

Reference to ISO 11040-6

Needle size29G Tapered Needle, 1/2"
Syringe barrel lubricationNone: Silicone oil-free

Needle shield


Rigid needle shield

Chloro butyl-diene blend polymer, Polypropylene

Flange shape

Cut flange

Reference to ISO 11040-6

Plunger stopper

i-coatingTM stopper

Reference to ISO 11040-5

Chloro butyl rubber (CIIR) with silicone resin coating


Barrel: 10 x 10 Nest/Tub format (100 syringes per tub) or 10 x 16 Nest/Tub format (160 syringes per tub)

Plunger stopper: Double Tyvek® bag or Rapid Transfer Port bag



Barrel: Autoclave (Steam)

Plunger stopper: Autoclave (Steam)

Plunger rodPolypropylene
OptionalFinger grip extension (Back stop)

Global Solutions

PLAJEX™ Ready-to-Fill Polymer Syringes with Tapered Needle are available to drug product manufacturers globally. For more information about product availability, specifications, and applicable standards, download our data sheet or contact your Terumo representative today.

Please note that some products may not be available in all regions, reach out to your local Terumo Medical Care Solutions - Pharmaceutical Solutions Division contact for details. All brand names are trademarks or registered trademarks owned by TERUMO CORPORATION, its affiliates, or unrelated third parties.


Relevant product information
PLAJEX Tapered Needle Leaflet_TMCS_2023


1 Assessment of the Injection Performance of a Tapered Needle for Use in Prefilled Biopharmaceutical Products, Krayukhina et al (2020) J Pharm Sc, 109: 515-523
2 Functional Evaluation and Characterization of a Newly Developed Silicone Oil-Free Prefillable Syringe System, Yoshino et al (2014) J Pharm Sc, 103: 1520-1528
3 Terumo’s PLAJEX and Nemera’s Safe’n’Sound: A Collaboration that Says You're in Safe Hands, Dierick et al, (2017) ONdrugDelivery, 73, 5-12
4 Polymer-based Pre-filled Syringes in Combination with a Two-Step Autoinjector, W. Dierick et al., ECA 2014

Let’s Find Your Best Solution

Innovation and creativity are central to our Pharmaceutical Solutions Division value proposition. Our expert teams lead the industry in developing and manufacturing advanced, high-performing infusion and injection technologies for all parenteral applications.

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This information is intended for professionals in the pharmaceutical supply chain who are interested in primary packaging, injection components and medical devices from Terumo Pharmaceutical Solutions, for use in combination with their respective drug products (hereafter, pharmaceutical professionals). Please note that the product information contained on this website is exclusively addressed to pharmaceutical professionals. This product information is not for the general public, nor is it intended to be a substitute for professional medical advice or for the care that patients receive from their healthcare professionals. By accessing it, you (i) acknowledge having read and understood both the above message and our terms of use and, further, (ii) confirm that you do so in the capacity of a pharmaceutical professional.