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Product Innovation

Innovation at Terumo

Terumo Medical Care Solutions, Pharmaceutical Solutions Division, uses innovation to meet the objectives of our group commitment to “Contributing to Society through Healthcare”. Together with leading pharmaceutical and biotechnology companies, we collaborate to develop and manufacture advanced parenteral drug delivery solutions and provide them with unique integrated CDMO services that can support improved patient treatment outcomes worldwide.
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Introduction
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Parenteral Drug Delivery
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Our Innovations
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Product Portfolio
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Regulatory Support
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Focus on Parenteral Drug Delivery Innovation
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We are focused on providing patient-centered solutions that integrate unique technologies with high-quality parenteral drug delivery technologies. We strive to transform medical care through the integration of high-quality device design, digital technologies, and the personalization of medicine.  Terumo Pharmaceutical Solutions also applies innovation to a host of services such as contract manufacturing and development organization (CDMO) services that efficiently bring new drugs to patients.
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Innovation from Terumo
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Terumo Pharmaceutical Solutions is continually creating innovations that solve the complex challenges faced when administering small molecule, vaccine, biologic and biosimilar products via parenteral drug delivery. Discover some of our latest parenteral product innovations below.
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Terumo Injection Filter Needle

Injection Needle

A first step of the INFINO™ Development Program

Our Terumo Injection Filter Needles are intended for hypodermic and intravitreal injections and include an integrated 5μm polyamide mesh filter in the hub, intended to prevent intrinsic and extrinsic particles from being injected into the patient. Designed to provide a needle developed to enable injection of parental fluids for treatment of a growing number of eye diseases such as neovascular age-related macular degeneration, diabetic retinopathy and retinal vein occlusions.

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PLAJEX™ COP Syringe with i-coating ™ Technology

Prefillable Syringe

Our PLAJEX™ Cyclo Olefin Polymer (COP) syringe represents a leap in primary packaging for sensitive drug formulations, particularly biologics. Its breakthrough i-coating ™ technology eliminates the need

for silicone oil, significantly reducing protein aggregation and particle formation. This innovation ensures drug integrity, enhances patient safety, and streamlines the development of new, complex therapies.

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PLAJEX™ Ready-to-Fill Polymer Syringe with Tapered Needle

Prefillable Syringe

Integrating proprietary tapered needle technology with a robust silicone oil-free polymer syringe, Terumo Medical Care Solutions – Pharmaceutical produced an advanced RTF polymer syringe system that reduces injection forces without compromising patient comfort. Featuring a polymer-based barrel with excellent strength and clarity, and Terumo - Pharmaceutical’s proprietary i-coating™ technology on the stopper, the silicone oil-free syringe system is designed to preserve sensitive biotherapeutics1.

1 Functional Evaluation and Characterization of a Newly Developed Silicone Oil-Free Prefillable Syringe System, Yoshino et al (2014) J Pharm Sc, 103: 1520-1528

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Nanopass 34G

Injection Needle

The Nanopass™ 34G is the world's thinnest double-tapered 34G pen needle1, redefining patient comfort for self-injections. Designed for the subcutaneous (SC) injection of therapeutics, including insulin and human growth hormones (HGH), Nanopass™ 34G offers the quality and supply reliability needed to meet drug developers’ toughest parenteral delivery challenges and product commercialization goals.   This product exemplifies our commitment to enhance the patient experience by using our core capabilities.

1 Based on research by Terumo Corporation in November 2020

Please note that Nanopass ™ 34G is not available in USA and Canada.

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ImmuciseIntradermal Injection System

Drug Delivery Device

Terumo’s Immucise™ Intradermal Injection System is designed to deliver vaccines and other approved drugs to the dermal layer of the skin for improved immune response in comparison to intramuscular or subcutaneous injections1.  The vertical type intradermal (ID) injection system is applied perpendicular to the skin of the deltoid region of the patient’s arm2.

1  Intradermal Delivery of Vaccines, A review of the literature and the potential for development for use in low- and middle-income countries, August 27, 2009

2 Shimizu, Sakiko et al. “Performance and usability evaluation of novel intradermal injection device Immucise™ and reanalysis of intradermal administration trials of influenza vaccine for the elderly.” Vaccine vol. 40,6 (2022): 873-879

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Terumo SurGuard3 Safety Hypodermic Needle

Injection Needle
The Terumo SurGuard™3 Safety Hypodermic Needle features an advanced, integrated safety mechanism designed to prevent needlestick injuries, which remain a significant concern in clinical settings. Its intuitive activation and clear sightline for aspiration demonstrate our commitment to user-friendly design combined with critical safety innovation.
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Terumo Product Portfolio
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Explore the entire portfolio of innovative parenteral healthcare solutions offered by Terumo Pharmaceutical Solutions.
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Regulatory Support - Bringing Innovation to Patients Globally
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Our regulatory experts help pharma and biotech customers bring their innovative therapies to global markets applying years of regulatory experience to every customer project. With filing ready data and documentation, Terumo Pharmaceutical Solutions regulatory experts help customers successfully navigate the complexities of drug-device combination filings or combination products required by leading regulatory bodies including the U.S. Food and Drug Administration (U.S. FDA), European Medicines Agency (EMA) and Pharmaceuticals and Medical Devices Agency (PMDA) and any local regulatory authorities. Learn more about Terumo’s regulatory support services.
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Connect with Our Experts for Tailored Support

Pharmaceutical and biotechnology companies partner with Terumo Pharmaceutical Solutions to bring medical innovations to life. If you have any questions about how Terumo Pharmaceutical Solutions can help you to develop, manufacture, and deliver your next parenteral drug product, reach out to us today.
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